Usher syndrome1/17/2024 The work will provide a solid foundation for understanding the function of each usherin isoform and developing an effective gene therapy platform to treat USH2A associated visual defects, she said in the news release. “Understanding which isoforms of usherin are expressed in the retina and the cochlea and what role they play (in contrast to mutant pathogenic forms) is essential in developing an effective gene therapy construct,” Naash said in the release. Naash has already cloned two usherin isoforms to be tested with her innovative platform to safely advance gene therapy for USH2A. To rescue vision loss, Naash’s non-viral therapy targets the mutation in usherin, the protein product that causes Usher Syndrome Type 2A. “Developing an effective treatment for USH2A has been challenging due to its large coding sequence (15.8 kb) that has precluded its delivery using standard approaches and the presence of multiple isoforms with functions that are not fully understood,” said Naash, who will also evaluate the long-term efficacy of the best therapeutic platform for future translation to the clinic, according to the news release. The Usher syndromes (USH) comprise genetically-related disorders that bring about simultaneous hearing loss and vision loss (resulting from an eye condition. Intravitreal treatment consists of injections directly into the vitreal chamber of the eye. Gene therapy is the introduction of a normal gene into cells to correct genetic disorders. “Our goal is to advance our current intravitreal gene therapy platform consisting of DNA nanoparticles/hyaluronic acid nanospheres to deliver large genes in order to develop safe and effective therapies for visual loss in Usher Syndrome Type 2A,” Naash said in the news release. RP affects the retina, the eye’s light-sensitive layer, leading to a breakdown of cells in the retina which causes blindness. Dunn Endowed Professor of biomedical engineering, $1.6 million to support her work.Īccording to a University of Houston news release, Usher Syndrome Type 2A, caused by mutations of the USH2A gene, can include hearing loss from birth and progressive loss of vision, prompting retinitis pigmentosa (RP). The National Eye Institute has awarded Muna Naash, PhD, John S. With the hopes it will restore vision loss in Usher Syndrome Type 2A (USH2A), a rare genetic disease.
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Joshua rush last name1/17/2024 Cyrus is in charge of producing videos for Jefferson Middle School, and he has chosen Jonah as his cameraman. He apologizes profusely for the terrible kiss, but he has no idea why he is not attracted to her. Cyrus is under pressure to kiss Iris, so he makes an awkward kiss on her lips. Cyrus then reveals to Buffy that he has a crush on Jonah. Despite the awkward first kiss with Iris, he tells his friends anyway in order to impress them. Cyrus demonstrates her ability to take on unreasonable dress codes by protesting them with The Good Hair Crew. Cyrus enlisted Buffy to help him appear more masculine in order to impress Jonah. Cyrus was the first to look at Bex’s secret baby picture when he went through Andi’s belongings in the Andi Shack.Ĭyrus is concerned about being girly after receiving a text from Jonah that says “Ur girly.” According to Jonah, he meant to say he was “grumpy,” but his words were corrected to girly. Dark brown hair, large brown eyes, and a mole on the cheek line his appearance. Cyrus Goodman, one of The Good Hair Crew‘s youngest members, is just 18 years old. Cyrus enjoys seeing all of the best in everyone and being open to new things. Cyrus has a variety of anxiety-related issues, as well as a lot of fears. Joshua Rush plays him in Disney’s first-ever main character to come out as gay. He has said that he hopes his character can help other kids who are struggling with their sexuality to feel seen and represented on television.Ĭyrus Goodman is a Disney character known for his role as Andi Mack. Since coming out, Joshua Rush has been an outspoken advocate for LGBTQ rights, just like his character Cyrus Goodman. In an emotional Instagram post, Joshua Rush shared that he had been struggling with his sexuality for years, but that he was finally ready to embrace it and live his truth. Many viewers have wondered if Cyrus Goodman is gay in real life, and the answer is yes! actor Joshua Rush came out as gay in 2019, shortly after his 18th birthday. Since the Disney Channel show Andi Mack premiered in 2017, the character of Cyrus Goodman has been an outspoken advocate for LGBTQ rights, even becoming the first openly gay character on a Disney Channel show. Matplotlib subplot rotate xticks1/17/2024 set_xticklabels ( for poll in polls ], rotation = 30 ) return figureīut if we do this, we're no longer telling the axes how many ticks there are, and so it reverts back to generating its own ticks. bar ( range ( len (polls ) ), for poll in polls ] )Īxes. set_title ( "Polls to their vote counts" )Īxes. How to create a custom legend with matplotlibįigure = plt. How to export one image with multiple plots with matplotlib.How to draw a stacked bar chart with matplotlib.How to adjust the x axis tick labels so they fit in the screen.How to adjust the size of a matplotlib plot.How to draw a bar chart with matplotlib.
Iphone 8 won t go into recovery mode1/17/2024 In such a situation, repair or replacement may be necessary. Water damage can lead to internal component corrosion, while physical damage can cause hardware problems.Īdditionally, physical damage, including a cracked screen or damaged logic board, can also prevent your phone from turning on. If your iPhone 8 has been exposed to water or physical damage, it may fail to power on. See also - Snapchat Keeps Crashing On Your Iphone? How To Fix It Water or Physical Damage This will erase all data on your device, so make sure to back up your data before restoring your iPhone 8. If force restarting your iPhone 8 doesn't work, you may need to restore your phone using iTunes. To do this, press and hold the power button and home button (or volume down button on models 7 or later) at the same time until the Apple logo appears on the screen. If your iPhone 8 is stuck in a boot loop, you may need to force restart your device. This issue typically occurs after a software update, where the phone gets stuck in a boot loop. Try cleaning the charging port with a soft-bristled brush or a toothpick to remove any dirt or debris that may be blocking the connection.Īnother common reason why your iPhone 8 won't turn on is due to software crashes or glitches. If the charging port is damaged or dirty, it may not be able to charge your phone properly. It's also possible that there is a problem with the charging port on your iPhone 8. In some cases, the problem may be as simple as a loose connection, which can be easily fixed by a professional. If you suspect that there is a hardware problem with your phone, you may need to take it to a repair shop to have it fixed. If your phone has been dropped or exposed to water, there may be damage to the internal components that is preventing it from turning on. Hardware ProblemsĪnother common reason why an IPhone won't turn on is because of hardware problems. If your iPhone 8 still doesn't turn on after charging it for a few minutes, try using a different charging cable or adapter to see if that solves the issue. It's important to note that if your iPhone 8's battery is completely drained, it may take a few minutes of charging before it turns on. If the battery health is below 80%, it may be time to replace the battery. You can check the battery health of your iPhone 8 by going to Settings > Battery > Battery Health. In some cases, the battery may need to be replaced. If your phone still won't turn on after charging it, there may be an issue with the battery itself. If the battery is completely drained, it may take up to an hour for the phone to turn back on. If your phone won't turn on, try plugging it into a charger and waiting a few minutes. One of the most common reasons why your phone won't turn on is because the battery is dead. Understanding these reasons can help you troubleshoot the problem and get your phone up and running again. It can be frustrating when your iPhone 8 won't turn on, but there are several common reasons why this might happen. See also - How To Remove Yourself From A Group Text Common Reasons Why iPhone 8 Won't Turn On This article will explore some of the common causes of an iPhone 8 not turning on and provide tips and solutions to help users get their phone back up and running. There are also several other steps users can take to try and fix an iPhone 8 that won't turn on. There are several reasons why your phone may not turn on, including software issues, hardware problems, or a drained battery. Having an iPhone 8 that won't turn on can be a frustrating experience for anyone. If the battery is completely drained, it may take some time to charge before the phone will turn on. One of the first steps is to check the battery level and ensure the iPhone 8 is charged. If an iPhone 8 is not turning on, it is important to troubleshoot the issue and try to determine the root cause. Medieval madness remake for sale1/17/2024 By using modern electronics, LED lighting, and today’s manufacturing technology, the game will provide the pinball experience you have grown to love along with the reliability and craftsmanship that is demanded in today’s pinball market.Īs with all of our pre-owned electronic pinball machines, this Medieval Madness Remake includes our 30 day warranty on the electronics. Monster Bash Remake was recreated to exceed the high standards of the original game. Medieval Madness is a whimsical return to a world of knights and castles, fire-breathing dragons and damsels-in-distress, magical wizards and treacherous trolls, a dazzling adventure sure to captivate players of all ages and skill levels. – Score Display upgraded to Full Color HD – Pin Stadium playfield illumination both sides of the playfield. Medieval Madness Pinball Machine Remake Color DMD Display Brand New 415.99 gameroomguys (67,957) 99.7 Buy It Now Free shipping 21 sold derosnopS Medieval Madness King of Payne Topper (Royal Edition) Chicago Gaming Company Brand New 4,000.00 (whammy) (1,479) 100 or Best Offer +23. In addition to this game looking and playing like it’s practically brand new, the owner had installed the following modifications valued at over $900! Home use only means that this game has never spent any time in a commercial location such as an arcade, bar or restaurant. It is a one owner, home use only game with less than 300 total plays on this game. This game has been well taken care of and it goes to show. This is it!Īcquiring from a collector that is downsizing we bring you this amazing condition Medieval Madness (Remake). If you are looking for one of, if not THE most collectible pinball machine. Medieval Madness (Remake) Pinball Machine – Pre-Owned * Roger mcguinn spouse1/17/2024 ^ "Roger McGuinn – Artist Chart History".^ "Roger McGuinn – Discography – Back from Rio".The Byrds: Timeless Flight Revisited (2nd ed.). ^ Gettelman, Parry (February 22, 1991).MusicHound Rock: The Essential Album Guide. Year-end charts 1991 year-end chart performance for Back from Rio Chart (1991) John Hall – demo engineer, mixing at Firetail-on-the-Hill StudiosĬharts Weekly charts Weekly chart performance for Back from Rio Chart (1991).David Cole – producer, engineer, mixing.Michael Thompson – electric guitar, acoustic guitar.Benmont Tench – organ, keyboards, Hammond B-3.Tom Petty – lead vocals ("King of the Hill"), backing vocals.Michael Penn – backing vocals, 12-string acoustic guitar.Roger McGuinn – lead vocals, backing vocals, 12-string electric guitar, 12-string acoustic guitar.John Jorgenson – acoustic guitar, electric guitar, baritone guitar, saxophone, bass guitar, mandolin.Chris Hillman – vocals, background vocals.David Cole – percussion, piano, acoustic guitar, MPC-60.Mike Campbell – electric guitar, slide guitar, baritone guitar."If We Never Meet Again" ( Jules Shear) – 4:28.Includes "Back from Rio Interlude" (Roger McGuinn, Tom Petty, Jeff Lynne)."Your Love Is a Gold Mine" (Roger McGuinn, Dave Stewart) – 4:06."The Time Has Come" (Scott Cutler, Roger McGuinn) – 3:45."Without Your Love" (Roger McGuinn, Camilla McGuinn) – 3:59. "King of the Hill" (duet with Tom Petty) (Roger McGuinn, Tom Petty) – 5:27."The Trees Are All Gone" (Roger McGuinn, Camilla McGuinn) – 3:51."Suddenly Blue" ( Scott Cutler, Roger McGuinn, Dennis Morgan) – 3:49." You Bowed Down" ( Elvis Costello) – 3:52."Someone to Love" ( Roger McGuinn, Camilla McGuinn) – 3:32.In Europe, Back from Rio was released in February 1991 and featured different cover artwork. Two singles were drawn from the album: "King of the Hill" and "Someone to Love", which peaked at #2 and #12 respectively, on the Billboard Hot Mainstream Rock Tracks chart. The album was generally well received by music critics and it peaked at No. Other prominent songwriters on the album-besides McGuinn and his wife Camilla-are Elvis Costello, Jules Shear and Dave Stewart of the Eurythmics. In addition, several members of the Heartbreakers provide musical backing on a number of the album's tracks. Also prominent on the album are Tom Petty and the Heartbreakers, with Petty co-authoring and duetting with McGuinn on the album's lead single "King of the Hill". The album was issued following the release of the Byrds box set and musically it leans on the sound of the Byrds thanks to McGuinn's ringing 12-string electric guitar and vocal contributions from ex-Byrds members David Crosby and Chris Hillman. It was released on January 8, 1991, more than a decade after McGuinn's previous solo album, Thunderbyrd. He has made such amount of wealth from his primary career as Singer-songwriter, Guitarist, Musician, Record producer.Back from Rio is the sixth studio album by American singer-songwriter, guitarist and co-founder of the Byrds Roger McGuinn. Roger McGuinn net worth or net income is estimated to be $30 Million dollars. His relationship status is single.įamily Information Parents Name Spouse Name N/A Children Name Number of Children(s) N/A Partner Name N/A Relative(s) Name Height 1.88 m ( 6′ 2″ ) Weight N/A Bust – Waist – Hip N/A Hair Color N/A Eye Color N/A Shoe Size N/Aīefore he was famous, After hearing Elvis Presley’s “Heartbreak Hotel,” he asked his parents for a guitar. Roger sun sign is Cancer and his birth flower is Water Lily.īirth date 13-Jul Day of Birth Monday Year of Birth 1942 Birth Sign Cancer Birth Sign Duality Passive Birth Sign Modality & Element Cardinal Water Opposite Sign Capricorn Roger McGuinn birthday is on 13-Jul-42 and he was born on Monday. Bio / Wiki Full Name Roger McGuinn Occupation Guitarist Age 80 Date of Birth JPlace of Birth Chicago, IL Star Sign Cancer Country United States Gender Male Windows 20131/16/2024 Internet access is also required to access documents stored on OneDrive, unless you install the OneDrive desktop app. For Microsoft 365 plans, internet access is also needed to manage your subscription account, for example to install Office on other PCs or to change billing options. However, internet access is required to install and activate all the latest releases of Office suites and all Microsoft 365 subscription plans. Other features of Microsoft Office 2013 Professional Plus are, however, far more convincing: the PDF editor offers greatly improved options for collaborative editing, there is cloud integration with Skydrive, and extras such as embedding YouTube videos, are great innovations.You don’t need to be connected to the internet to use Office applications, such as Word, Excel, and PowerPoint, because the applications are fully installed on your computer. Many selection elements and options are too small for untrained fingers. Unfortunately, the Office Suite is anything but tablet-friendly. Microsoft Office 2013 Professional Plus comes with many useful functions, which lets it be selectively used on touch screen devices. Microsoft Office 2013 Professional Plus uses the same minimalist tile design as Windows 8, and everything seems to mold together well. Large, cleanly arranged icons are there for the most important functions, while new templates provide visually appealing spreadsheets and presentations.Ĭonclusion: improved all-round Office Suite All of the applications come with new touch-optimized viewing modes. In addition to images, you can embed videos via HTML code in Microsoft Office 2013 Professional Plus. The famous ribbon bar is expanded only when necessary and it's optimized for finger operation on touch screens. When you use Microsoft Office 2013 Professional Plus, you'll realize that there have been some changes. Touch-optimized use and minimalist design à la Windows 8 E-mails in Outlook 2013 are now tablet friendly and can be viewed, if you want, in an optimized list view with larger areas. In all views, Outlook 2013 brings together fade-in menus for appointments, contacts and tasks. On Tablets, you can switch between slides using finger gestures, paint with a stylus for a lecture on film, or use a virtual laser pointer. Besides the presentation itself, you can also see a bullet list and more details on the presenter screen. PowerPoint 2013 splits the presenter mode into two different views for the audience and the presenter. The new Quick Analysis feature in Microsoft Office 2013 lets you preview certain formatting options in the spreadsheet itself. Excel also makes it easier to create pivot tables and graphics by generating suggestions in a similar fashion. Excel analyzes the entire table, detects relations between cells, and suggests a value or text. In Excel 2013, the new Flash Fill function automatically fills out a range of selected cells. Microsoft Office 2013 Professional Plus also edits PDFs without the need for additional software, which makes it a direct competitor of Adobe Acrobat. Making changes to documents has had a huge overhaul, and expanded to make editing documents easier. With the new touch-optimized reading mode in Word 2013, you can skim through documents using a finger swipe. Shadowsocksx ios1/16/2024 VPNCity only offers it for Windows devices. It prevents user data from leaking in Germany online by terminating the regular internet connection. The connection gets established if both seem safe.īesides automatic protection, you get options to use OpenVPN safe tunneling in Germany or SoftEther with a virtual network adapter for VPN connection flexibility.Īnother significant feature we found was the kill switch that protects user information and activities when the VPN connection stops working suddenly. It determines the connection safety for your device by reviewing both parties. On top of this, it uses RSA-4096 handshake encryption to mask user data even before it goes online. It provides military-grade AES-256-bit encryption, considered the best for data confidentiality. VPNCity covers all your security essentials. Well, yes! The top concern of users in Germany we get comes in the form: is VPNCity safe to use? Security and Features - Is VPNCity secure In Germany? Moreover, it takes no time to select a server in Germany or switch between them when needed. The interface is neatly divided for searching servers by streaming options, location, and a customizable favorites tab. However, its server connectivity service is appreciable. We can only select from the minimum options of countries, raising issues while streaming in Germany or any other service unavailable in the region. Here’s an overall look at VPNCity servers:Īlthough it has over 3000 servers to prevent overcrowding, it spans only 33 countries, which is limited coverage. The maximum distribution is settled in Europe with 24 servers, then the American region with 12 servers, and 3 servers each in the other two regions. It covers regions in Europe, America, the Middle East/Africa, and Asia. VPNCity has a small-sized network with 3,167 servers spread in 33 countries and 44 cities worldwide. Server Network - How many servers does VPNCity have? You may check our list of the best cheap VPNs in Germany that are reliable and don’t cost a fortune. It may not stand at a competitive edge with the top few VPNs, but it still offers quality services and essential features. Its 2-year plan can be given a try for only $1.69 each month, which is one of the cheapest rates in the industry currently. It charges lesser than most premium VPNs in Germany and provides reasonable services. Overall, we have found its pricing to be nominal compared with the services it offers. You can try the VPNCity 1-month plan to test how it goes. You can subscribe to any plan and pay via PayPal and credit cards in Germany. It has a 30-day money-back guarantee and a 7-day free trial for Android phones. You can avail of 70% off on the ongoing plans. Like most VPNs in Germany, the longer the subscription plan, the lesser its cost gets. VPNCity offers three pricing plans in Germany to its customers.
Universe sandbox 2 barycenter1/16/2024 4 - Select the Barycenter and the remaining star (the Sun). The download was scanned for viruses by our system. It may sharply differ from the full version of the program due to the license type. #UNIVERSE SANDBOX 2 BARYCENTER FULL VERSION# 5 - Click on the Binary orbit button again. Universe Sandbox 2 Game Overview Free Download Compressed Specs Screenshots PC RIP Torrent/uTorrent Type of game: Simulation PC Release Date: AugDeveloper/Publishers. The application could use some direct objectives, as the player is left to grasp for fun. It is an attempt meant to emulate the emptiness of space but that falls short. Universe Sandbox Legacy is the first entry in the series. It does not exceed expectations, as number 2 completely redid the engine of the game and graphics improved it immensely. Space Engine is an option for a universe sandbox. This game mostly focuses on exploring the various planets rather than playing with how the physics of the world operate. Also, Space Engine is free while Universe Sandbox 2 is not. The Sandbox gives the player an interesting experience with controlling space while teaching a bit about physics. It is not too hard to pick up, but it lacks any direct purpose. Nonetheless, it is a fun experience and is worth trying out.Learn about space and play with planets in Universe Sandbox 2 (US2). Create your own galaxies and defy the laws of physics. On YouTube people are playing universe sandbox 2 but I cant find it on Steam theres only universe sandbox which I presume is the first one. You can clearly see if there’s water or lava on the surface of a planet from far away.īut on Google theres even a universe sandbox 3 so I dont understand it I want the latest one the best one.įor how smooth this game runs, its graphics are highly fine-tuned and detail. How to Download IOS Android Universe Sandbox 2 on Mobile Click on the “Download Game” button. Download “Universe Sandbox 2” Installer (Supports Resumable Downloads). Open the Installer, Click Next, and choose the directory where to Install. Universe Sandbox is a physics-based space simulator. It merges gravity, climate, collision, and material interactions to reveal the beauty of our universe and the fragility of our planet. Create, destroy, and interact on a scale you've never before imagined. Universe Sandbox is all about asking fantastical what-if questions. #UNIVERSE SANDBOX 2 BARYCENTER SOFTWARE#.#UNIVERSE SANDBOX 2 BARYCENTER ZIP FILE#.#UNIVERSE SANDBOX 2 BARYCENTER FULL VERSION#. Gerber multi tool repair1/16/2024 This directed, accurate force shows up in cutting as well as carving. With a solid grip below and my thumb on the blade’s spine, I could apply significant pressure without losing edge (or tip) control. While the metal used is far from legacy quality, the Gerber Armbar Drive is a solid choice for light- to moderate-duty repair, cutting, and snipping chores. In short: Even without the other tools, the steady blade and agile driver of this pocket-size multitool make it worth carrying around the house or into the backcountry. It also has enough carbon content to spark a ferro rod with moderate effort while remaining corrosion-resistant. Here, “catalog spec” and “real-life” match one-to-one, as the Armbar behaves more like a dedicated folding knife. Listed at 2.5 inches, the extended-and-locked knife configuration gives full access to the blade’s entire length. On the pocketknife side, a single, plain-edge 5CR15MoV stainless blade waits inside the truss-like frame. The Portland-based toolmaker positions the Armbar as a way to “get your multitool out of the truck and into your pocket.” Solid marketing copy but, in our testing, it undersells where this model performs, both at home and in the field. Why? It displaces more expensive options while replacing the need to carry common tools on foot, bike, in a pack, or in the cab (of anything). Gerber Armbar Drive brings big utility to common home repair and backcountry travel scenarios on a pocket-size budget.Īt under $40 and with three color options, Gerber takes a big risk putting the Armbar Drive on the marketplace. AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |